适度/剧烈活动对绝经后妇女3年身体组成变化的影响:一个目标试验模拟试验
Jiarui Li1, Jennifer W Bea2, Michael LaMonte3
1Epidemiology and Biostatistics, University of California Irvine, Irvine, CA, United States.
American journal of epidemiology
|July 11, 2024
概括
遵守体育活动指南有助于绝经后妇女改善身体组成. 定期适度活动可以减少腹部脂肪,增加瘦组织,促进更好的健康结果.
科学领域:
- 老年学是一门学科.
- 运动生理学 运动生理学
- 公共卫生 公共卫生
背景情况:
- 绝经后的女性经历了显著的身体组成变化,增加了心脏代谢风险.
- 腹部脂肪组织 (AAT) 沉积模式是这种风险的关键因素.
- 有限的证据表明,在这个人口群体中,体育活动对AAT的具体影响是有限的.
研究的目的:
- 模拟一个目标试验,对AAT和身体组成的3年变化评估身体活动干预措施.
- 评估绝经后妇女体育活动和身体组成之间的剂量反应关系.
- 为了比较遵守2018年美国人身体活动指南 (≥150分钟/周) 与没有干预的效果.
主要方法:
- 分析了4451名来自妇女健康倡议 (WHI) 队列的绝经后妇女 (50-79岁).
- 使用重复的全身双X射线吸收仪 (DXA) 扫描来获得内脏 (VAT) 和皮下脂肪组织 (SAT).
- 模拟了一个使用参数-g公式的目标试验,以估计AAT和身体组成在3年中的平均变化.
主要成果:
- 增加中度体力活动显示AAT,总体脂肪和体重的剂量依赖性减少.
- 坚持≥150分钟/周的适度活动与VAT,SAT和总体脂肪的显著减少有关.
- 在遵循指南的体力活动水平的情况下,观察到总瘦软组织的显著增加.
- 对于强烈强度活动干预措施,也发现了类似的有益模式.
结论:
- 身体活动指南的遵守与绝经后妇女身体组成的显著改善有关.
- 有针对性的体力活动干预措施可以有效地减轻更年期后不良的身体组成变化.
- 这些发现支持促进体育活动,以减少该人口中的心脏代谢风险.
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