揭示TIM-3基因多态化在全源造血干细胞移植中的潜力 - 一项初步研究

Sylwia Biały1, Jagoda Siemaszko1, Małgorzata Sobczyk-Kruszelnicka2

  • 1Laboratory of Clinical Immunogenetics and Pharmacogenetics, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wroclaw, Poland.

Transplant immunology
|July 11, 2024
PubMed
概括

在T细胞免疫球蛋白和含有-3 (TIM-3) 的粘素域中的遗传变异可以影响血造干细胞移植 (HSCT) 的结果. 特定的TIM-3多态可能会降低急性移植对宿主疾病的风险,并影响移植后的细胞巨乳病毒感染率.

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