白物质基板是中国儿童发育性阅读障碍的基础形态意识缺陷
Xiaoyu Xu1, Xiaojing Song1, Lizi Lin2
1Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong, China.
概括
患有中国发育性阅读障碍的儿童在对形态意识至关重要的区域表现出白质差异. 这些差异,特别是在右下前囊中,与他们的语言缺陷有关.
科学领域:
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
- 语言学的语言学.
背景情况:
- 形态意识 (MA) 缺陷是中国发育性阅读障碍症 (DD) 的一个关键特征.
- 患有DD的儿童中潜在的白质变化在很大程度上仍未被探索.
研究的目的:
- 调查与中国儿童DDDD中MA缺陷相关的白质基质.
- 为了比较DD和典型发育 (TD) 的儿童之间的这些基质.
主要方法:
- 扩散张力成像 (DTI) 和对MA的认知测试对34名DD和42名TD儿童进行.
- 线性回归分析检查了MA和DTI指标,通道异常和群体相互作用之间的相关性.
主要成果:
- 马与右下前筋 (IFO),下纵向筋 (ILF),双侧乳头-头骨 (T_OCC) 和左弧形筋 (AF) 相相关.
- 与TD儿童相比,DD儿童在右IFO和T_OCC中表现出较低的轴向扩散率 (AD).
- 观察到右侧IFO和MA的分数异构性 (FA) 和辐射扩散性 (RD) 之间的显著相互作用,特别是在DD组中.
结论:
- 患有DD的中国儿童在腹部 (右IFO) 和视觉空间 (右T_OCC) 航道中表现出轴突退化,与他们的MA赤字有关.
- 中国MA依赖于腹腔,视空间和背部白质道.
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