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Updated: Jun 21, 2025

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检测化学物质暴露引起的代谢变化的策略,从大量特定条件的代谢模型中检测,这些代谢模型是使用计数技术计算的

Louison Fresnais1,2, Olivier Perin3, Anne Riu3

  • 1UMR1331 Toxalim (Research Centre in Food Toxicology), Université de Toulouse, INRAE, ENVT, INP-Purpan, UPS, Toulouse, France. louison.fresnais@loreal.com.

BMC bioinformatics
|July 11, 2024
PubMed
概括

本研究引入了一种计算方法来分析omics数据,减少信息过载,通过建模代谢网络来识别化学作用机制 (MoA). 这种方法有助于毒理学家了解化学物质对细胞代谢的影响.

关键词:
基于约束的建模.图形分析分析图形分析代谢作用机制的作用机制代谢建模 代谢建模有毒基因组学转录学数据集成数据集成

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