人类贝贝西亚 (Babesia odocoilei) 和巴托内拉 (Bartonella spp.) 的种类. 在美洲的共同感染
Ricardo G Maggi1, Ana Cláudia Calchi2, Charlotte O Moore1
1College of Veterinary Medicine, North Carolina State University, Intracellular Pathogens Research Laboratory Comparative Medicine Institute, Raleigh, NC, USA.
Parasites & vectors
|July 11, 2024
概括
贝贝西亚 (Babesia odocoilei) 感染在人类中比以前认为的更为常见,通常与巴托内拉 (Bartonella) 种类一起发生. 分子诊断证实了慢性症状患者的这些并发感染.
科学领域:
- 载体传播的传染病 载体传播的传染病
- 分子诊断学 分子诊断学
- 微生物学 微生物学
背景情况:
- 与Babesia和Bartonella物种的同时感染在理解载体传播疾病方面提出了复杂的挑战.
- 慢性,非特异性疾病通常与这些共同感染有关,影响疾病动态和流行病学.
- 以前对个体病原体影响的理解正在与共感染数据一起演变.
研究的目的:
- 为在美洲的人类提供Babesia odocoilei感染的分子证据.
- 为了突出Babesia odocoilei和Bartonella物种感染的频繁同时发生.
- 为了提高对载体传播疾病共致病的理解.
主要方法:
- 利用先进的分子诊断技术进行敏感的检测.
- 采用了分子方法的组合来准确确认.
- 专注于呈现慢性,非特异性症状的患者.
主要成果:
- 在七个患有慢性症状的个体中确认了Babesia odocoilei感染.
- 在7例巴贝西亚阳性病例中的6例中,确定了与一种或多种巴贝贝拉菌共同感染.
- 证明了敏感分子诊断在识别这些感染中的实用性.
结论:
- 贝贝西亚奥多科伊利的感染似乎比以前认为的更为普遍.
- 与巴托内拉菌种的同时感染是与Babesia odocoilei.相关的重要因素.
- 对共感染的进一步研究对于精确诊断和治疗载体传播疾病至关重要.
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