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Updated: Jun 21, 2025

Isolation of Primary Mouse Hepatocytes for Nascent Protein Synthesis Analysis by Non-radioactive L-azidohomoalanine Labeling Method
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Published on: October 23, 2018

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O-GlcNAcylated RALY通过调节USP22 mRNA核出口来促进肝细胞癌细胞的增殖

Shiwei Liu1, Qingpeng Lv2, Xinyu Mao2

  • 1School of Medicine, Southeast University, Nanjing 210009, China.

International journal of biological sciences
|July 12, 2024
PubMed
概括

研究人员确定RALY是肝细胞癌 (HCC) 的致癌因子. O-GlcNAcylation稳定了RALY,通过RALY/USP22mRNA轴促进了HCC细胞的增殖,RALY-PROTACs显示了治疗潜力.

关键词:
这是一种O-GlcNAcylation.拉力会的时间.肝细胞癌是肝细胞癌.核出口mRNA的核出口酸蛋白解酶向的木乃伊.

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