口服抗瘤治疗需要什么? 对患者和从业人员的偏好进行分析
Anna Hester1, Franziska Henze1, Anna Marie Debes1
1Department of Obstetrics and Gynecology, Breast Center and Comprehensive Cancer Center (CCC) Munich, University Hospital, LMU Munich, Munich, Germany.
Frontiers in oncology
|July 12, 2024
概括
患者和医疗保健提供者更喜欢口服治疗转移性乳腺癌,而不是化疗. 口服治疗提高生活质量和坚持,支持长期使用CDK4/6抑制剂.
科学领域:
- 在瘤学瘤学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 自2016年以来,CDK4/6抑制剂已经改变了激素受体阳性,HER2阴性转移性乳腺癌的治疗方法.
- 基于内分泌的疗法,通常是口服的,提供化学疗法的替代方案,具有不同的副作用概况.
- 口服旨在优化疗效,治疗持续时间,患者独立性和生活质量.
研究的目的:
- 分析患者和从业人员对不同治疗方法和时间表的偏好.
- 为了比较口服治疗与化疗与日常生活的兼容性.
- 了解患者和从业人员对管理副作用和长期癌症治疗的坚持的看法.
主要方法:
- 一个单心分析,涉及25名护士/医生和51名患者 (接受内分泌单疗法,内分泌疗法或静脉化疗) 的问卷.
- 使用四点利克特比例或双向响应选项来评估偏好.
- 数据分析侧重于不同治疗组的同意分数和不同治疗组之间的比较.
主要成果:
- 患者和从业人员都强烈喜欢口服治疗,而不是其他形式的管理 (利克尔特尺度1.3和1.4,分别).
- 接受口服治疗的患者报告与接受化疗的患者相比,与日常生活的兼容性显著更好 (1.6/1.7与2.6).
- 医生更喜欢连续的口服方案,而患者在连续和21/7方案之间没有显著的偏好,除非出现严重的副作用 (CTCAE 3级).
结论:
- 口服抗瘤疗法,包括连续和21/7疗法,被患者和从业人员都喜欢.
- 有效的患者教育和治疗管理对于管理副作用和确保高坚持至关重要.
- 在转移性乳腺癌中使用CDK4/6抑制剂长期治疗期间维持生活质量可以通过首选的口服施用途径和支持性护理来实现.
关键词:
21/7 饮食方式 21/7 饮食方式这是一种CDK4/6抑制剂.连续治疗方案 连续治疗方案在线医疗服务 (e-health)转移性乳腺癌 转移性乳腺癌口服治疗是一种口服疗法.患者教育 患者教育患者的偏好,患者的偏好.更多相关视频
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