2000年至2019年冰岛患者的移植:结果是否受到低体积的影响?
Thordur P Palsson1, Margret B Andresdottir2, Eirikur Jonsson1
1Divison of Urology, Surgical Services, Landspitali University Hospital, Reykjavik, Iceland.
Frontiers in transplantation
|July 12, 2024
概括
冰岛的移植结果显示患者和移植的生存率很高,与国际标准相比. 这证明了他们国家移植计划的成功,即使在少数人群中也是如此.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植手术 移植手术
- 公共卫生 公共卫生
背景情况:
- 冰岛的脏移植历来只在Landspitali大学医院 (LUH) 进行了有限的活体供体 (LD) 程序.
- 直到最近,已故供体移植主要在国外进行.
- 本研究评估了冰岛患者移植的结果.
研究的目的:
- 评估冰岛患者移植的结果.
- 评估移植后患者和移植的存活率.
- 确定一个小国家的全国移植计划的可行性.
主要方法:
- 对2000年至2019年间接受脏移植的所有冰岛居民的回顾性研究.
- 数据来源于冰岛末期病登记,LUH医疗记录和Scandiatransplant数据库.
- 利用CKD-EPI和修改的施瓦茨方程来估计膜过率;卡普兰-梅尔方法用于生存分析.
主要成果:
- 在221名患者中进行了229次移植;58.9%来自活体捐赠者 (LD).
- 在LUH进行了118次移植 (51.5%),其中116次来自LDs.
- 患者10年生存率为87.7%,死亡审查的移植存活率为89.2%.
结论:
- 冰岛脏移植患者和移植患者的存活率与国际主要移植中心的存活率相当.
- 这些发现支持在一个小国家内建立和维持高质量的移植计划的可行性.
- 与大型国际中心的合作是提高国家移植能力的成功模式.
相关概念视频
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