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Updated: Jun 21, 2025

A High-content In Vitro Pancreatic Islet β-cell Replication Discovery Platform
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XBP1拼接有助于内细胞网膜压力诱导的人类小岛粉样蛋白多上调节

Yun Zhang1, Susan Lin2, Jing Yao1

  • 1National Clinical Research Center for Geriatric Disorders, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

Genes & diseases
|July 12, 2024
PubMed
概括

细胞内膜网膜 (ER) 的压力通过激活X盒结合蛋白1 (XBP1) 拼接,提高了人类β细胞中小岛氨基多 (IAPP) 的表达. 阻止这种途径可以改善β细胞的功能和存活率,从而提供对2型糖尿病的见解.

关键词:
细胞内膜网膜应激压力是什么岛屿粉样蛋白聚酸.2型糖尿病是什么? 2型糖尿病是什么?在XBP1中使用.在β细胞中,β细胞的功能.

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