脑癌患者的手术血栓预防:一个经济模式
F Jeffrey Lorenz1, Brandon J Martinazzi2, Neerav Goyal1
1Department of Otolaryngology-Head and Neck Surgery Penn State Hershey Medical Center Hershey Pennsylvania USA.
OTO open
|July 12, 2024
概括
手术后静脉血栓栓塞 (VTE) 发生在1.3%至2.5%的头癌患者中. 常规化疗预防与肝素或素是潜在的成本效益,以预防VTE.
科学领域:
- 在瘤学瘤学.
- 血管外科 血管外科
- 卫生经济学 卫生经济学
背景情况:
- 接受手术的头癌 (HNC) 患者面临静脉血栓栓塞 (VTE) 的风险.
- 在这种人群中,VTE化学预防的成本效益需要评估.
研究的目的:
- 量化HNC患者手术后静脉瘤发作的发生率.
- 评估使用化疗预防 (肝素和素) 预防VTE的经济影响.
主要方法:
- 通过TriNetX研究网络,使用来自53个医疗机构的数据进行回顾性成本效益分析.
- 在接受部剖析 (2012-2022) 的HNC患者中确定了VTE的发病率.
- 分析了化疗预防和VTE的成本,以确定平衡绝对风险降低 (ARR).
主要成果:
- 手术后静脉动脉瘤的发病率为1.3% (部切割) 和2.5% (部切割与自由翻盖).
- 在没有化疗预防的HNC患者中,文献报告的平均VTE率为3.8%.
- 氨酸和氨酸在达到0.05%和0.14%的ARR时具有成本效益,同时具有可接受的出血并发症风险.
结论:
- 手术后静脉瘤发病率在HNC患者之间有所不同.
- 常规化疗预防用肝素或素显示,在HNC患者中预防VTE的潜在成本效益.
更多相关视频
13:37A Mouse Tumor Model of Surgical Stress to Explore the Mechanisms of Postoperative Immunosuppression and Evaluate Novel Perioperative Immunotherapies
Published on: March 12, 2014
30.0K
05:49Modeling the Effects of Hemodynamic Stress on Circulating Tumor Cells using a Syringe and Needle
Published on: April 27, 2021
2.6K
相关概念视频
Cancer Survival Analysis
340
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
340
Anticoagulant Drugs: Low-Molecular-Weight Heparins
672
Hemostasis is a crucial process that prevents excessive blood loss from damaged blood vessels. It involves various mechanisms such as vasoconstriction, platelet adhesion and activation, and fibrin formation. The importance of each mechanism depends on the type of vessel injury. In contrast, thrombosis is the abnormal formation of a blood clot within the blood vessels, leading to potential complications if the clot obstructs blood flow. Thrombosis can be caused by increased coagulability of the...
672
Cancer Therapies
7.6K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
7.6K
