相关实验视频
Updated: Jul 12, 2026
07:48
An Orthotopic Bladder Cancer Model for Gene Delivery Studies
Published on: December 1, 2013
12.5K
什么是膀癌分子亚型? - 对应点 - 对应点
François Radvanyi1, Francisco X Real2,3,4, David McConkey5,6,7
1Equipe Oncologie Moléculaire, Equipe Labellisée Ligue Contre le Cancer, CNRS, UMR144, Institut Curie, PSL Research University, Paris, France.
Bladder cancer (Amsterdam, Netherlands)
|July 12, 2024
概括
这项研究认为,分类膀癌分子亚型需要的不仅仅是细胞身份. 考虑到瘤微环境和进化,为更好的治疗方法提供了临床上有用的见解.
科学领域:
- 在瘤学瘤学.
- 癌症生物学 癌症生物学
- 分子病理学分子病理学
背景情况:
- 膀癌分子亚型对于治疗至关重要.
- 目前的分类方法主要侧重于瘤细胞的身份.
研究的目的:
- 为了呈现一个对比,只专注于瘤细胞的身份,膀癌的分类.
- 突出额外参数对临床有用的瘤分类的重要性.
主要方法:
- 对现有的膀癌分类策略进行审查和批判性分析.
- 强调将空间,时间和微环境因素纳入其中.
主要成果:
- 新生细胞的特征很重要,但对于全面的膀癌分类是不够的.
- 瘤微环境和空间/时间变化提供关键数据.
- 瘤异质性和在治疗压力下的进化是关键考虑因素.
结论:
- 需要对膀癌分类采取整体方法.
- 整合瘤微环境和进化动态可以提高临床效用.
- 未来的分类系统应该包括超越细胞身份的更广泛的参数范围.
相关概念视频
01:23Urinary Bladder
The urinary bladder is a hollow, muscular sac that temporarily stores urine before it is expelled from the body. It can hold approximately 600 mL of urine prior to micturition. The bladder is retroperitoneal and located behind the pubic symphysis in the pelvic floor.
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
In males, the bladder is situated in front of the rectum, while in females, it is positioned anterior to the vagina and uterus. The bladder floor contains an inverted triangular area called the trigone, defined by the two ureteric...
01:19Anatomy of the Genitourinary System II: Bladder and Urethra
The lower urinary system consists of the urinary bladder and urethra, which are essential in storing and expelling urine from the body. Together with the internal and external sphincters, these structures work together to regulate urination effectively.Anatomy of the BladderThe urinary bladder is a muscular, stretchable organ behind the pubic bone and in front of the rectum. In females, the bladder is positioned anterior to the vagina and inferior to the uterus, while in males, it is located...