对PTSD进行MDMA辅助的简短认知行为联合治疗:试点研究试点研究的研究协议.
L A Morland1,2,3, D Perivoliotis2,3, T R Wachsman2
1Department of Veterans Affairs National Center for PTSD Women's Health Sciences Division, 150 South Huntington Street, Boston, MA, 02130, USA.
Contemporary clinical trials communications
|July 12, 2024
概括
这项研究探讨了MDMA辅助疗法与简短的认知行为联合疗法 (bCBCT) 相结合,以改善创伤后应激障碍 (PTSD) 的退伍军人的关系功能. 这项研究旨在提高退伍军人和他们的伴侣的治疗结果.
科学领域:
- 精神病学是一个精神病学.
- 心理学 心理学 心理学
- 临床研究 临床研究
背景情况:
- 创伤后应激障碍 (PTSD) 显著影响个人和关系福祉,特别是在面临军事压力因素的退伍军人夫妇中.
- 虽然简短的认知行为联合治疗 (bCBCT) 有效地减少了PTSD症状,但它对关系功能的影响是可变的.
- 改善PTSD治疗的关系结果对于退伍军人的整体健康至关重要,MDMA辅助疗法显示出增加bCBCT等现有干预措施的潜力.
研究的目的:
- 评估结合MDMA辅助治疗与BCBCT的初步疗效,安全性和可接受性,用于患有PTSD的退伍军人和他们的伴侣.
- 调查这种综合方法在改善PTSD症状严重程度和关系功能方面的潜力.
- 在退伍军人事务医疗保健系统中试行一个可扩展的治疗模式.
主要方法:
- 这是一项开放式,单一地点的研究,涉及8名患有PTSD的退伍军人和他们的亲密伴侣 (N=16).
- 治疗团队提供了bCBCT与两个MDMA辅助治疗会话相结合.
- 在MDMA后进行了两次情感集中整合会议,评估了PTSD症状和关系功能.
主要成果:
- 将收集关于MDMA辅助bCBCT的疗效,安全性和可接受性的初步数据.
- 这项研究将提供对PTSD症状严重程度的影响的初步见解.
- 将评估关系运行结果的变化.
结论:
- 这是研究MDMA辅助BCBCT改善PTSD和关系功能在美国退伍军人和他们的伴侣的第一个研究.
- 这些发现可以为VA医疗保健系统中治疗PTSD的可扩展模型提供信息.
- 这种方法可以为合作伙伴提供下游的好处,增强个人和关系的功能.
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