神经PASC患者的认知功能:疲劳,情绪和住院状态的作用
Joshua Cahan1,2,3, John-Christopher A Finley4, Erica Cotton1,2,4
1Northwestern Medicine, Davee Department of Neurology, Chicago, IL, United States.
Frontiers in neurology
|July 12, 2024
概括
在SARS-CoV-2感染 (Neuro-PASC) 神经学急性后续症状中的认知问题更多地受到疲劳和情绪的影响,而不是住院状态. 主观认知问题仍然存在,这凸显了在神经PASC患者中管理这些症状的必要性.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 认知科学 认知科学
背景情况:
- 感染SARS-CoV-2的神经后急性后果 (Neuro-PASC) 可能会影响认知功能.
- 了解与神经PASC认知障碍相关的因素对于患者管理至关重要.
- 之前的COVID-19住院治疗对神经PASC认知结果的作用需要进一步调查.
研究的目的:
- 在患有神经PASC的成人门诊患者中描述认知功能.
- 调查主观/客观认知功能和之前的COVID-19住院治疗之间的关联.
- 探索疲劳和情绪症状对神经PASC认知投诉的影响.
主要方法:
- 106名患有神经PASC的成人门诊患者接受了缩短的神经心理评估.
- 用患者报告结果测量信息系统 (PROMIS) 自我报告来评估主观认知障碍.
- 客观认知表现通过综合评分来评估;使用PROMIS也评估了疲劳和情绪症状.
主要成果:
- 主观认知障碍比客观发现更明显,并与疲劳和情绪症状有关.
- 疲劳独立地解释了主观认知评级中最多的差异 (17.51%).
- 既没有客观的,也没有主观的认知障碍与之前的COVID-19住院相关,在调整疲劳和症状发作后.
结论:
- 缩短的神经心理评估可能无法在Neuro-PASC的初始查之外检测出客观认知缺陷.
- 在Neuro-PASC中,主观认知问题似乎是持久的,受疲劳和情绪的影响,无论住院时间如何.
- 对于神经PASC患者的认知投诉,需要对管理疲劳和情绪进行进一步的研究.
关键词:
在 COVID-19 疫情中,长时间的COVID.焦虑是一种焦虑.有关认知性的认知.抑郁 抑郁症 抑郁症 抑郁症 是一种疲劳 疲劳 疲劳 疲劳 疲劳 疲劳住院治疗 住院治疗在SARS-CoV-2感染 (PASC) 的后急性后果.更多相关视频
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