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人类测量用于预测青少年心脏代谢疾病风险因素
Luyu Xie1,2, Joohan Kim2,3, Jaime P Almandoz4
1Department of Epidemiology, Human Genetics and Environmental Sciences, University of Texas Health Science Center at Houston, School of Public Health, Dallas, Texas, USA.
Obesity (Silver Spring, Md.)
|July 12, 2024
概括
腰比,腰围和BMI百分位数更好地预测青少年的心脏代谢风险,而不是身体脂肪百分比. 这些预测因种族和种族而异,需要量身定制的查方法.
科学领域:
- 青少年健康 青少年健康
- 评估心脏代谢风险评估
- 公共卫生 公共卫生
背景情况:
- 青少年慢性疾病的早期查对于使用人体测量测量来识别有风险的个体至关重要.
- 这些测量对不同种族和民族的心脏代谢风险因素的预测准确性仍然不确定.
研究的目的:
- 评估身体质量指数 (BMI) 百分位数,总体脂肪百分比,腰围 (WC) 和腰比 (WHR) 对青少年心脏代谢风险因素的预测性表现.
- 评估不同种族和种族群体的预测能力如何不同.
主要方法:
- 从2017-2018年国家健康和营养检查调查 (NHANES) 中对12至19岁的个体进行横截面分析.
- 利用接收器操作特征 (ROC) 曲线来评估BMI百分位数,总体脂肪百分比,WC和WHR对高血压,高血糖症,高三糖血症和低高密度脂蛋白 (HDL) 胆固醇的预测能力.
- 分析了西班牙裔,非西班牙裔黑人 (NHB),非西班牙裔白人 (NHW) 和其他/多种族群体的预测性表现.
主要成果:
- 与总体体脂肪百分比 (AUC=0.56) 相比,WHR (AUC=0.77),WC (AUC=0.77) 和BMI百分比 (AUC=0.73) 是高血压的优越预测因素.
- 体重指数百分位在预测高甘油三血症 (AUC=0.70对0.59) 和低高脂胆固醇 (AUC=0.69对0.59) 中的准确性高于总体脂肪百分比.
- 预测准确性因种族和种族而异;与西班牙裔和NHB青少年 (0.77) 相比,NHW青少年血压升高的AUC最高 (0.89). 总体脂肪百分比在西班牙裔青少年 (0.73) 与NHW青少年 (0.58) 中更好地预测低HDL胆固醇.
结论:
- WHR,WC和BMI百分位是青少年心脏代谢风险因素的更有效的预测因素,而不是总体脂肪百分比.
- 种族和民族之间的预测准确度的显著差异强调了在青少年健康查中需要量身定制的风险评估策略.
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