相关实验视频

Updated: Jun 21, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors

Published on: October 26, 2015

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CDK2的抑制剂和PROTACs:挑战和机遇

Yangjie Zeng1, Xiaodong Ren1, Pengyao Jin1

  • 1Medical College, Guizhou University, Guiyang, China.

Expert opinion on drug discovery
|July 12, 2024
PubMed
概括

循环素依赖性激酶2 (CDK2) 抑制剂通过向不受控制的细胞增殖,对癌症治疗有希望. 然而,选择性和毒性方面的挑战需要进一步的研究,以获得有效的临床应用.

关键词:
在CDK2中使用CDK2.这就是PROTAC.这就是为什么SAR SAR SAR.癌症 癌症 癌症 癌症 癌症抑制剂抑制剂的使用

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