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儿科肝移植中的外科流体管理:系统性审查

Raihanita Zahra¹, Andi Ade Wijaya Ramlan¹, Christopher Kapuangan¹

¹Universitas Indonesia Faculty of Medicine, Department of Anaesthesiology and Intensive Care, Central Jakarta, Indonesia.

Turkish journal of anaesthesiology and reanimation

|July 12, 2024

概括

在儿科肝移植 (LT) 中的外科流体管理影响了结果. 与哺乳期的Ringer相关的死亡率更高.

科学领域:

儿科手术儿科手术
移植医学移植医学
临界护理医学临界护理医学

背景情况:

在儿科肝移植 (LT) 中,外科流体管理是复杂的,有可能导致并发症和不稳定.
关于流体管理和输血对儿科LT死亡率和发病率的影响的研究有限.

研究的目的:

系统地审查关于儿科LT患者周术流体管理和临床结果的证据.
确定流体管理策略与患者结果之间的关联.

主要方法:

系统审查英语初级研究关于儿科LT的外科流体管理.
搜索了PubMed,EBSCOHost,Embase,Proquest和谷歌学者 (开始时间至2023年12月19日).
通过Joanna-Briggs研究所的检查清单评估偏见风险;通过叙述合成结果.

主要成果:

包括五项优质的回顾性队列研究.
与乳酸环球 (LR) 与正常盐水相关的较高死亡率,而不是大规模输血 (MT).
较长的住院时间与MT,阳性液体平衡 (>20%在72小时内) 和高的手术内血液制品的使用有关.
随着更高的手术内流体的使用,血栓形成的风险增加.
在手术期间的MT和LR输注与30天的移植损失和功能障碍的增加有关.

结论:

术后流体管理显著影响了儿科LT接受者的结果.
需要进一步的研究,以建立最佳的流体管理和评估策略,为儿科LT.
研究结果强调了流体平衡和输血实践在儿科肝移植护理中的关键作用.

关键词:

孩子孩子孩子孩子流体管理流体管理肝移植肝移植肝移植死亡率死亡率

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