中国老年人的骨肌肉质量和功能:一个横截面研究
1Department of Nephropathy, Shenzhen Luohu Hospital of Traditional Chinese Medicine, Guangdong, P.R. China.
Renal failure
|July 12, 2024
概括
恶化功能与中国成年人低骨肌量 (LSMM) 的风险更高有关. 患有轻度功能障碍的老年男性更有可能患上LSMM.
科学领域:
- 老年学是一门学科.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 肌肉骨健康 肌肉骨健康
背景情况:
- 功能对整体健康至关重要,功能受损与各种健康并发症有关.
- 骨肌肉质量是健康和功能能力的重要指标,特别是在老年人中.
研究的目的:
- 调查估计的膜过率 (eGFR) 与中国成年人低骨肌量 (LSMM) 的患病率之间的关联.
- 探索该协会中潜在的性别差异.
主要方法:
- 来自中国健康与退休纵向研究 (CHARLS) 的3726名中国成年人的横截面研究.
- 用2021年CKD-EPI方程计算eGFR时使用血清肌素.
- 使用BMI调整的肌肉质量来评估LSMM,并使用后勤回归模型来分析eGFR和LSMM风险之间的关联.
主要成果:
- 恶化功能 (较低的eGFR) 与两种性别的LSMM风险增加有显著关联.
- 与女性相比,轻度功能障碍的男性参与者对LSMM的倾向较高,尽管这种差异在严重的功能障碍中并不显著.
- 观察到eGFR与LSMM风险之间存在显著的非线性关系.
结论:
- 降低功能是中国成年人中低骨肌肉质量的重要危险因素.
- 与女性相比,患有轻度功能不全的老年男性患LSMM的风险似乎更高.
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