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具有ICOS表达性的调节性T细胞影响抗瘤CTL群体的组成

Nikoletta Diamantopoulos1,2, Joanna Li1,2, Antoine Bouchard1,3

  • 1Institut de Recherches Cliniques de Montréal, Montreal, Quebec, Canada.

Journal of immunology (Baltimore, Md. : 1950)
|July 12, 2024
PubMed
概括

在小鼠中从调节性T细胞 (Tregs) 中去除ICOS可以减少黑色素瘤瘤的生长. 这表明Tregs上的ICOS可能会抑制抗瘤免疫力,影响癌症免疫治疗策略.

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