Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Mass Spectrometry: Carboxylic Acid, Ester, and Amide Fragmentation01:01

Mass Spectrometry: Carboxylic Acid, Ester, and Amide Fragmentation

1.2K
The fragmentation patterns observed for compounds such as carboxylic acids, esters, and amides in the mass spectra include ⍺-cleavage and McLafferty rearrangement. Fragmentation by ⍺-cleavage preferentially occurs at the carbon-carbon bond at the ⍺-position next to the carboxylic group to generate a neutral radical and a cation. Long chain compounds with hydrogen at their γ-carbon undergo McLafferty rearrangement to give a radical cation and a neutral alkene.
For example,...
1.2K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Dual human milk oligosaccharide-fibre utilisation is a selection cue for the weaning gut microbiome.

Nature communications·2026
Same author

Degradation of mucin <i>O</i>-glycans by a human gut symbiont requires a complex enzyme repertoire and promotes colonization.

bioRxiv : the preprint server for biology·2026
Same author

The butyrate-producing Gram-positive human gut bacterium, Hoskinsella mucinilytica, selectively targets host mucin N-acetylhexosamines.

The Journal of biological chemistry·2026
Same author

Resources for screening the literature for glycan-related terms using PubAnnotation in GlyCosmos.

Glycobiology·2026
Same author

Glycosphingolipids in human abdominal leiomyosarcoma and liposarcoma.

The Journal of biological chemistry·2026
Same author

Mass spectrometric profiling reveals alterations in N-Glycans and O-Glycans in Tay-Sachs disease under Autophagy-Induced conditions.

Glycoconjugate journal·2025

相关实验视频

Updated: Jun 21, 2025

Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments
10:59

Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments

Published on: February 7, 2025

967

UniCarb-DB:一个MS/MS实验性葡萄糖碎片数据库

Chunsheng Jin1, Vignesh Venkatakrishnan2, Kristina A Thomsson1

  • 1Proteomics Core Facility at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

Methods in molecular biology (Clifton, N.J.)
|July 12, 2024
PubMed
概括
此摘要是机器生成的。

UniCarb-DB是一个糖性谱图书馆,可以帮助研究人员从质谱数据中识别糖结构. 该资源通过提供可搜索的双重质谱 (MS/MS) 光谱数据库来促进糖化学研究.

关键词:
数据库数据库数据库是一个数据库.糖甘的结构结构格莱科姆糖的使用方法橄糖化物 橄糖化物后翻译修改后的修改.谱图库是一种光谱图书馆.质谱测量质量谱测量

更多相关视频

The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides
08:37

The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides

Published on: November 2, 2021

2.2K
Improved In-gel Reductive &#946;-Elimination for Comprehensive O-linked and Sulfo-glycomics by Mass Spectrometry
13:06

Improved In-gel Reductive β-Elimination for Comprehensive O-linked and Sulfo-glycomics by Mass Spectrometry

Published on: November 20, 2014

11.8K

相关实验视频

Last Updated: Jun 21, 2025

Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments
10:59

Glycomics-Guided Glycoproteomics Facilitates Comprehensive Profiling of the Glycoproteome in Complex Tumor Microenvironments

Published on: February 7, 2025

967
The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides
08:37

The Application of Open Searching-based Approaches for the Identification of Acinetobacter baumannii O-linked Glycopeptides

Published on: November 2, 2021

2.2K
Improved In-gel Reductive &#946;-Elimination for Comprehensive O-linked and Sulfo-glycomics by Mass Spectrometry
13:06

Improved In-gel Reductive β-Elimination for Comprehensive O-linked and Sulfo-glycomics by Mass Spectrometry

Published on: November 20, 2014

11.8K

科学领域:

  • 格莱科米克斯 (Glycomics) 是一个有趣的药物.
  • 质谱测量质量谱测量
  • 生物化学 生物化学

背景情况:

  • 糖基化是一种关键的翻译后修饰,影响细胞功能.
  • 葡萄糖体,包括细胞或组织中的所有葡萄糖体,是复杂的,难以分析的.
  • 现有的甘氨酸资源需要有效的数据管理和分析工具.

研究的目的:

  • 介绍UniCarb-DB,一个全面的光谱图书馆,用于糖化学品.
  • 为质谱 (MS) 实验人员提供一种用于糖结构阐明的工具.
  • 加强将甘氨酸数据集成到研究工作流程中.

主要方法:

  • 开发一个光谱库 (UniCarb-DB),包含超过1500条MS/MS碎片数据.
  • 包含每个条目的元数据,实验条件和生物来源.
  • 甘氨酸结构与GlyTouCan存储库的关联,以获得更广泛的资源.

主要成果:

  • 目前,UniCarb-DB拥有超过1000个独特的甘氨酸结构.
  • 该数据库支持MS实验人员直接使用MS数据将MS数据转换为结构信息.
  • 在线搜索工具可以浏览异构结构并执行峰值匹配搜索.

结论:

  • 通过提供强大的光谱库,UniCarb-DB显著推进了糖化学研究.
  • 该数据库通过先进的MS工具促进了定量和定性糖性成分的分析.
  • UniCarb-DB的设计是为了与商业和开放访问的MS软件无集成.