退伍军人患有并发性失眠和抑郁情节的痴呆症诊断的时间
Melanie L Bozzay1, Hannah E Joyce2, Lan Jiang3
1Department of Psychiatry and Behavioral Health, The Ohio State University Wexner Medical Center, Columbus, OH, USA.
Journal of Alzheimer's disease : JAD
|July 12, 2024
概括
患有心力衰竭,失眠和抑郁症的老年人面临痴呆的最高风险. 早期查这些疾病可以帮助及时干预和管理.
科学领域:
- 老年学是一门学科.
- 神经学 神经学
- 心脏病学 心脏病学
背景情况:
- 患有心力衰竭的老年人患阿尔茨海默病和相关痴呆症 (AD/ADRD) 的风险增加.
- 失眠和抑郁症发作与AD/ADRD风险有关,但它们的组合和连续影响仍然不清楚.
研究的目的:
- 调查心力衰竭患者患有并发性失眠和/或抑郁情节的痴呆症诊断时间.
主要方法:
- 从203,819名被诊断患有心力衰竭的退伍军人队伍中分析了二次数据.
- 利用了来自129个VA医疗中心的数据.
主要成果:
- 患有失眠和抑郁症的患者在1年 (HR=1.43) 和3年 (HR=1.40) 的随访中显示出最短的痴呆症诊断时间.
- 这种增加的风险与患有一种或两种并发症的患者相比较.
结论:
- 伴随性失眠和抑郁症显著缩短了心力衰竭患者痴呆症发病的时间.
- 对这些并发症的查可以识别高风险个体,以加强痴呆症监测和早期干预.
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