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Updated: Jun 21, 2025

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
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Published on: March 11, 2016

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合格的损伤生物标志物在早期临床药物开发过程中表现出价值

Kodihalli C Ravindra1, Kelly A Fader2, David Potter3

  • 1Department of Drug Safety Research and Development, Pfizer Inc., Groton, CT 06340, United States.

Toxicological sciences : an official journal of the Society of Toxicology
|July 12, 2024
PubMed
概括

这项研究表明,FDA合格的脏生物标志物小组在早期试验中有效地识别了药物诱导的损伤 (DIKI). 该小组帮助健康志愿者和患者群体对新疗法进行风险评估和临床决策.

关键词:
致毒性 致毒性 致毒性脏管状损伤 脏管状损伤有资格的生物标志物.安全性降低了风险.

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