儿科急性胰腺炎第一次发作后的营养参数
Sarah Orkin1, Phillip Holovach2, Tyler Thompson3
1Department of Pediatrics, College of Medicine, University of Cincinnati, USA; Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, USA.
Clinical nutrition ESPEN
|July 12, 2024
概括
儿童在急性胰腺炎 (AP) 后经常出现营养缺乏症,包括低素,脂溶性维生素和白素. 严重的AP (SAP) 与BMI降低,维生素E缺乏以及糖尿病风险增加有关.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 营养科学 营养科学
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 急性胰腺炎 (AP) 可能导致营养不足.
- 在单个AP事件后,这些缺陷在儿童中的患病率尚未得到充分确立.
研究的目的:
- 确定儿童在第一次入院后的人类测量和实验室基础营养缺陷的患病率.
主要方法:
- 对儿科患者 (≤21岁) 进行前性观察队列研究,他们的第一个AP发作.
- 在AP开始时和AP后3个月和12个月收集的人类测量和实验室数据.
- 分类AP严重程度为轻度,中度或重度 (SAP).
主要成果:
- 随访了181名儿童;13%的儿童在12个月内发展为糖尿病前期或糖尿病.
- 接近三分之一的孩子在3个月或12个月时患有低费里丁水平;8%的孩子在12个月时患有维生素A缺乏.
- 超过一半的人患有维生素D不足/缺乏;24%的人在3个月后患有低白蛋白.
结论:
- 儿童在AP后经历各种营养缺陷,包括费里丁,脂溶性维生素和低白蛋白.
- 严重的AP (SAP) 与BMI Z-score降低,更高的维生素E缺乏,以及糖尿病前期/糖尿病风险增加相关.
- 建议在AP后对营养标志物进行连续监测.
相关概念视频
Acute Pancreatitis II: Clinical Manifestations and Management
118
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
118
Chronic Pancreatitis II: Collaborative Care
84
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Assessment:
84
Acute Pancreatitis I: Introduction
353
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
353
Chronic Pancreatitis I: Introduction
86
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
86
Enteral Nutrition II: Nasointestinal and Gastrostomy Feeding
103
Enteral nutrition encompasses various methods of delivering nutrition directly to the gastrointestinal (GI) tract, bypassing traditional oral intake. It is particularly beneficial for patients who cannot eat by mouth but have a functioning digestive system. Key methods include nasointestinal feeding, gastrostomy, and jejunostomy, each suited to different clinical scenarios based on the patient's needs and condition.
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
Nasointestinal Feeding
Nasointestinal feeding involves placing a tube...
103
Overview of Protein Metabolism
977
Proteins are broken down into amino acids during digestion. Unlike fats and carbohydrates, which are stored for later use, proteins are not. Instead, amino acids are either used to produce ATP through oxidation or contribute to the creation of new proteins for the growth and repair of the body. Any surplus amino acids from the diet are converted into glucose or triglycerides rather than excreted.
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
Amino acids play various roles in the body once they are absorbed into cells. They are restructured...
977


