患有偏头痛和肉症的患者之间的关联:一项回顾性研究
Dong Ah Lee1, Ho-Joon Lee2, Jinseung Kim3
1Department of Neurology, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea.
Medicine
|July 12, 2024
概括
这项研究发现,在偶发性偏头痛患者和健康对照人群之间,肌厚度 (TMT) 没有差异,这是肉症的标志物. 结果表明,在患有偶发性偏头痛的人群中,没有证据表明有性偏头痛.
科学领域:
- 神经学 神经学
- 老年学是一门学科.
- 放射学 放射学是一门学科.
背景情况:
- 肌肉质量丧失的萨尔科佩尼亚,在神经疾病中越来越多地被认可.
- 插曲性偏头痛 (EM) 是一种流行的神经疾病,具有潜在的系统影响.
- 时间肌肉厚度 (TMT) 是一种潜在的成像生物标志物,用于 Sarcopenia.
研究的目的:
- 通过使用时肌厚度 (TMT) 来调查患有偶发性偏头痛 (EM) 的患者的肉类的存在.
- 为了比较EM患者和健康对照者之间的TMT.
- 根据偏头痛光环的存在或不存在来分析EM患者的TMT.
主要方法:
- 根据STROBE指南进行的回顾性观察研究.
- 包括82名EM患者和53名健康对照.
- 大脑MRI使用3D T1加权成像来计算TMT.
主要成果:
- 在EM患者和健康对照者之间没有发现TMT的显著差异 (P = .801).
- 在患有和没有偏头痛光环的EM患者之间,TMT没有差异 (P = .569).
- 在TMT和EM的临床特征之间没有观察到相关性.
结论:
- 这项研究发现,在经过TMT评估的偶发性偏头痛患者中,没有发现软骨的统计证据.
- 与对照人群相比,部肌肉厚度似乎不是在EM患者中 Sarcopenia 的区分标记.
- 进一步的研究可能会探索其他潜在的标记物或与偏头痛肌肉健康相关的潜在机制.
相关概念视频
01:29Bone Disorders
3.5K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.5K
01:19Psychoneuroimmunology: Diabetes and Cancer
27
Chronic stress has been linked to both the onset and progression of serious health conditions, including Type 2 diabetes and cancer. Type 2 diabetes, a widespread chronic illness, is closely associated with obesity and insulin resistance, both of which often worsen under stress. Studies indicate that men experiencing high levels of chronic stress face a 45% higher risk of developing diabetes compared to those with minimal stress. Stress triggers physiological responses that elevate blood...
27
01:28Disorders of the Skeletal Muscle
927
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
927
01:20Myasthenia Gravis: Overview and Treatment
1.3K
Myasthenia gravis is a neuromuscular transmission disorder characterized by weakness and increased fatigability of skeletal muscles. It is an autoimmune disease affecting approximately one in 2000 people, where antibodies against the α1 subunit of nicotinic acetylcholine receptors are produced.
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
These antibodies interfere with the function of the nicotinic receptors in three ways: by binding to the receptor and disrupting acetylcholine binding; by causing cross-linking of receptors which...
1.3K
01:26Cross-bridge Cycle
117.2K
As muscle contracts, the overlap between the thin and thick filaments increases, decreasing the length of the sarcomere—the contractile unit of the muscle—using energy in the form of ATP. At the molecular level, this is a cyclic, multistep process that involves binding and hydrolysis of ATP, and movement of actin by myosin.
117.2K