相关实验视频
Updated: Jun 21, 2025

10:43
Dissection of Larval Zebrafish Gonadal Tissue
Published on: April 26, 2017
10.3K
比较基因组学揭示了鱼的型和性别染色体进化
Jiahong Wu1, Fujiang Liu2, Jie Jiao1
1Integrative Science Center of Germplasm Creation in Western China (Chongqing) Science City, MOE Key Laboratory of Freshwater Fish Reproduction and Development, School of Life Sciences, Southwest University, Chongqing 400715, China.
Cell genomics
|July 12, 2024
概括
软骨鱼 (chondrichthyes) 呈现出缓慢的染色体进化和保存的X染色体,这表明鱼性染色体在1.81亿年前的共同起源.
科学领域:
- 基因组学就是基因组学.
- 进化生物学 进化生物学
- 对比性卡里奥学 (Karyology) 的研究
背景情况:
- 软骨鱼 (chondrichthyes) 对于理解脊椎动物进化至关重要.
- 之前的研究缺乏全面的基因组数据来进行比较性型分析.
研究的目的:
- 为了分析六种德里希物种的基因组合成.
- 为了重建氏体的祖先型.
- 为了研究鱼性染色体的进化.
主要方法:
- 对六个染色体水平的孔德里希基因组进行比较基因组分析.
- 合成分析以确定染色体重组.
- 选择鱼物种的性别染色体表征.
主要成果:
- 孔德里希提亚人表现出慢速的染色体进化,在鱼,滑板动物和金像鱼中独立发生的融合事件.
- 孔德里希特族的祖先拥有类似原脊椎动物的型,具有18个微染色体对.
- 在鱼中保存的X微染色体表明,大约1.81亿年前的共同性染色体起源.
- 鱼的性别染色体表现出对剂量敏感基因的局部剂量补偿,而不是全球补偿.
- 鱼Y染色体与X的差异很大,有一个小的共同区域.
结论:
- 鱼染色体进化的特点是保存的特征和独立的重排.
- 这项研究提供了关于脊椎动物性染色体的古代起源和演变的见解.
- 了解鱼的性别染色体进化有助于更广泛的脊椎动物进化基因组学.
相关概念视频
The Ratio of X Chromosome to Autosomes
8.5K
In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female...
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female...
8.5K
Synteny and Evolution
3.2K
John H. Renwick first coined the term “synteny” in 1971, which refers to the genes present on the same chromosomes, even if they are not genetically linked. The species with common ancestry tend to show conserved syntenic regions. Therefore, the concept of synteny is nowadays used to describe the evolutionary relationship between species.
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
Around 80 million years ago, the human and mice lineages diverged from the common ancestor. During the course of evolution, the ancestral...
3.2K
Evolutionary Relationships through Genome Comparisons
5.7K
Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
5.7K
The Y Chromosome Determines Maleness
6.6K
The Y chromosome is a sex chromosome found in several vertebrates and mammals, including humans. In addition to 22 pairs of autosomes, the human males have one X chromosome and one Y chromosome. In these organisms, the presence or absence of the Y chromosome determines the development of male traits.
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size....
Evolution
Around 300 million years ago, the two sex chromosomes diverged from two identical autosomal chromosomes. Over time, the Y chromosome has lost most of its genes, shrinking in size....
6.6K
X and Y Chromosomes
25.8K
Among mammals, the gender of an organism is determined by the sex chromosomes. Humans have two sex chromosomes, X and Y. Every human diploid cell has 22 pairs of autosomes and one pair of sex chromosomes. A human female has two X chromosomes, while a male has one X chromosome and one Y chromosome.
The germline cells such as egg and sperm cells carry only half the number of chromosomes, i.e., 22 autosomes and one sex chromosome. All eggs have an X chromosome, while sperm cells can carry an X or...
The germline cells such as egg and sperm cells carry only half the number of chromosomes, i.e., 22 autosomes and one sex chromosome. All eggs have an X chromosome, while sperm cells can carry an X or...
25.8K
Convergent Evolution
27.7K
Evolution shapes the features of organisms over time, ensuring that they are suited for the environments in which they live. Sometimes, selection pressure leads to the rise of similar but unrelated adaptations in organisms with no recent common ancestors, a process known as convergent evolution.
27.7K

