在不同的潮呼吸频率下,使用大模拟方法评估呼吸空气流动的不稳定性
Hao Jing1, Haiwen Ge2, Hui Tang3
1School of Aerospace Engineering, Huazhong University of Science and Technology, Wuhan, 430074, China.
Computers in biology and medicine
|July 12, 2024
概括
了解不稳定的呼吸空气流是吸入颗粒和药物的关键. 呼吸频率显著影响空气流动力学,流和能源消耗,影响颗粒沉积.
科学领域:
- 流体动力学 流体动力学
- 呼吸系统生理学 呼吸系统生理学
- 气溶科学是一门气溶科学.
背景情况:
- 不稳定的呼吸道空气流对于粒子沉积和药物在呼吸道中的输送至关重要.
- 不同频率的呼吸道流速和眼球运动的变化使空气流分析复杂化.
研究的目的:
- 研究呼吸频率对不稳定的空气流特征的影响.
- 分析压力场,功率损失,模式模式和结构.
- 了解眼球运动在能量消耗和空气流转换中的作用.
主要方法:
- 使用大模拟来研究空气流动力学.
- 分析包括压力场,功率损失,模态空间模式和结构.
- 用模态分解和光谱来描述流动模式.
主要成果:
- 呼吸频率显著改变空气流动的不稳定性,流和流消散.
- 压力下降和眼球的流量遵循一个权力定律关系,特别是在低频率.
- 眼球运动在吸气和呼气期间不同地影响能量消耗,可以通过多项式函数来预测.
结论:
- 模态分解对于研究呼吸流是有效的,建议对吸入和呼气进行单独的分析.
- 主导的模态空间分布是呼吸流的特征,并且依赖于频率.
- 喉腔运动和缓慢的呼吸延迟了上呼吸道的过渡,突出了呼吸系统生理学对空气流的影响.
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