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Updated: Jun 21, 2025

Sample Preparation for Metabolic Profiling using MALDI Mass Spectrometry Imaging
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通过有效结合MALDI成像和LC-MS/MS,增强现场空间蛋白质学

Frederike Schäfer1, Archana Tomar2, Shogo Sato3

  • 1Faculty of Medicine, Department of Molecular Biology, Biomedical Center Munich, Ludwig-Maximilians Universität München, Munich, Germany; Protein Analysis Unit, Faculty of Medicine, Biomedical Center Munich, Ludwig-Maximilians Universität München, Munich, Germany; Institute for Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany; Environmental Epigenetics Group, German Center for Diabetes Research (DZD), Munich, Germany.

Molecular & cellular proteomics : MCP
|July 12, 2024
PubMed
概括

这项研究引入了一种新的方法,结合了质谱成像和液体色谱-并联质谱,用于高分辨率的空间蛋白质组学. 该方法加速了组织内的细胞分子差异的分析,有助于疾病研究.

关键词:
数据集成数据集成数据集成有牙的吉鲁斯.图像质谱仪的质谱仪.激光捕捉微解剖技术的微解剖空间蛋白质组学 空间蛋白质组学

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