高分辨率MRA脑血管发现在三族人群中
Rafael Rehwald1, Carole H Sudre2,3,4, Lorna Smith5
1From the Neuroradiological Academic Unit (R.R., M.S., H.R.J.), Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, University College London London, UK r.rehwald@ucl.ac.uk.
AJNR. American journal of neuroradiology
|July 12, 2024
概括
这项研究发现,南亚人患内动脉狭窄症的患病率更高,这是大脑MRI上常见的偶然发现. 威利斯 (CoW) 圈中的变化也因性别和种族而有显著差异.
科学领域:
- 神经成像是一种神经成像.
- 血管神经学 血管神经学
- 人口健康 人口健康
背景情况:
- 大脑MRI和威利斯圆 (CoW) 变异的偶然发现很常见.
- 之前的研究指出了种族差异,但很少有人在多民族队列中检查了这两项发现.
- 高分辨率的3T TOF-MRA能够对脑血管结构进行详细的评估.
研究的目的:
- 在英国三民族人口中描述偶然的脑血管发现和Cow形态.
- 更新这些发现的流行率估计.
- 为Cow提供形态参考值.
主要方法:
- 利用了来自英国Southall和BrentREvisited研究 (2014-2018) 的数据.
- 评估了750名参与者 (白人欧洲人,南亚人,非洲人加勒比人) 使用3T大脑MRI.
- 分析了飞行时间的MRA血管图 (TOF-MRA) 偶然发现和Cow解剖学.
主要成果:
- 偶然的脑血管发现发生在11.2%的参与者身上.
- 内动脉狭窄症在南亚人中最为普遍 (OR 2.72-2.79与其他群体相比).
- 在女性 (25.22%) 和非洲加勒比人 (34.86%) 中,完全的Cow更频繁.
结论:
- 内动脉狭窄症的患病率与种族独立相关,特别是在南亚人中.
- 大脑动脉瘤的患病率超过了之前的人口研究报告的患病率.
- 跨性别和种族存在Cow配置的显著解剖学差异.
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