提升的TyG指数与2型糖尿病老年患者中维生素D缺乏的风险增加有关
Qunyan Xiang1,2, Hu Xu1,3, Youshou Liu1,2
1Department of Geriatrics, The Second Xiangya Hospital of Central South University, Changsha, 410011, Hunan, China.
患有2型糖尿病和高甘油三糖指数 (TyG) 的老年患者面临维生素D缺乏症 (VDD) 的风险增加. TyG指数可以预测这个人群中的VDD.
科学领域:
- 内分泌学 在内分泌学.
- 代谢障碍 代谢障碍 代谢障碍
- 营养科学 营养科学
背景情况:
- 维生素D缺乏 (VDD) 与2型糖尿病 (T2DM) 和胰岛素抵抗 (IR) 有关.
- 甘油三糖指数 (TyG) 是胰岛素耐药性的标志物.
研究的目的:
- 调查老年T2DM患者的TyG指数和VDD风险之间的关联.
- 为了确定TyG指数是否可以预测这个人口中的VDD.
主要方法:
- 一项涉及572名老年T2DM参与者的研究.
- 计算TyG指数: ln [禁食甘油三 (mg/dL) × 禁食血糖 (mg/dL) /2].
- VDD定义为血清25-基维生素D [25(OH) D] <50nmol/L;使用多变量逻辑回归分析的关联.
主要成果:
- 在TyG指数和25(OH) D水平之间观察到显著的负相关性.
- 在最高的TyG四分位数中,参与者患VDD的风险增加了2.40倍 (P<0.001).
- 在多个混因素调整后,这种关联仍然很重要.
结论:
- 在老年T2DM患者中,TyG指数与维生素D水平有负相关.
- 在这个人群中,较高的TyG指数是VDD的重要预测指标.
- TyG指数可能在VDD的病理生理学中发挥作用.
更多相关视频
12:59Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
10:46A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
相关概念视频
Diabetes Mellitus: Type 2 and Gestational
Diabetes: Symptoms, Diagnosis, and Complications
Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Diabetes: Management and Pharmacotherapy
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Carbohydrate Metabolism
Starch accounts for approximately 60% of the carbohydrates consumed by humans. Since amylase enzymes cannot function in the stomach's acidic environment, starch can only be digested in the mouth and small intestine. Simple sugars are found naturally in milk and fruits in...
Vitamins
