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Updated: Jun 21, 2025

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
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Published on: May 25, 2018

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精确的体内RNA基编辑,使用波动增强的圆形CLUSTER指导RNA编辑

Philipp Reautschnig1, Carolin Fruhner1, Nicolai Wahn1

  • 1Interfaculty Institute of Biochemistry, Faculty of Science, University of Tübingen, Tübingen, Germany.

Nature biotechnology
|July 12, 2024
PubMed
概括

工程RNA基编辑使用G•U摇摆基对来显著减少非目标编辑. 这一进步提高了治疗RNA编辑的精度,提高了基因操纵的安全性和效率.

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