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Updated: Jun 21, 2025

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微海绵药物输送系统 (MSDDS) 的准备,随后进行扩大规模的方法

S Halder1, U S Behera2, S Poddar3,4

  • 1Department of Pharmaceutical Technology, Jadavpur University, Kolkata, 700032, India.

AAPS PharmSciTech
|July 12, 2024
PubMed
概括

研究人员开发了用于皮肤应用的新型5-甲 (5FU) 微球 (MS). 优化的配方实现了高的药物捕获和持续释放,显示了药物开发的前景.

关键词:
5 - - 甲酸是一种5甲.面中心的中央复合材料设计矩阵.微海绵内置的凝和扩展规模.

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Factors Affecting Dissolution: Particle Size and Effective Surface Area01:23

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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