相关实验视频

Updated: Jul 18, 2026

Novel Atomic Force Microscopy Based Biopanning for Isolation of Morphology Specific Reagents against TDP-43 Variants in Amyotrophic Lateral Sclerosis
13:31

Novel Atomic Force Microscopy Based Biopanning for Isolation of Morphology Specific Reagents against TDP-43 Variants in Amyotrophic Lateral Sclerosis

Published on: February 12, 2015

8.8K

没有C端域的TDP-43相分离的生物物理特征

Tommaso Staderini1,2,3, Alessandra Bigi1, Clément Lagrève1,4

  • 1Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, 50134, Florence, Italy.

Cellular & molecular biology letters
|July 12, 2024
PubMed
概括

与子类似的无域TDP-43通过液-液相分离 (LLPS) 形成液滴,与经历液-固相分离 (LSPS) 的全长TDP-43不同. 这阐明了控制神经退行性疾病中TDP-43相分离的静电力.

关键词:
静电学 静电学 静电学这就是LLPS.液态液态相隔离器 液态液态相隔离器液体固相分离的方法运动神经元疾病 运动神经元疾病RNA结合蛋白质是RNA结合的蛋白质.自动组装自动组装

更多相关视频

Use of Capillary Electrophoresis Immunoassay to Search for Potential Biomarkers of Amyotrophic Lateral Sclerosis in Human Platelets11:03

Use of Capillary Electrophoresis Immunoassay to Search for Potential Biomarkers of Amyotrophic Lateral Sclerosis in Human Platelets

Published on: February 10, 2020

7.3K
Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae07:14

Optogenetic Phase Transition of TDP-43 in Spinal Motor Neurons of Zebrafish Larvae

Published on: February 25, 2022

6.0K

相关概念视频

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)01:20

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...