用于预测静脉关口关闭后直肠静脉再泄漏的概率的诺莫图:一项回顾性研究
Yuegang Li1, Gang Hu1, Jinzhu Zhang1
1Department of Colorectal Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, China.
BMC cancer
|July 12, 2024
概括
在口腔关闭后识别直肠静脉性再泄漏的危险因素至关重要. 新辅助性化疗,显著的血液损失和特定的手术技术增加了重新泄漏的风险,有助于患者风险分层.
科学领域:
- 结肠直肠手术 结肠直肠手术
- 手术瘤学手术瘤学
- 瘤学的结果
背景情况:
- 直肠静脉性再泄漏是一种重要的术后并发症.
- 确定预测因素对于改善直肠癌手术和口腔闭塞后患者的治疗结果至关重要.
研究的目的:
- 为了确定直肠门闭塞后直肠门再泄漏的独立风险因素.
- 开发和验证一个预测模型,以检测直肠静脉动脉再泄漏.
主要方法:
- 对129名患有直肠癌的患者进行了回顾性分析,这些患者经历了静脉口腔泄漏后的静脉口腔关闭.
- 多变量分析以确定独立的风险因素.
- 开发一种名图表,用于预测静脉膜再泄漏的概率.
主要成果:
- 在13.2%的患者中,出现了解剖器性再泄漏.
- 确定了独立的危险因素:新辅助化学放射治疗 (OR 4.07),血液损失>50毫升 (OR 4.52) 和间切除 (OR 6.85).
- 一个名图显示出良好的预测准确性 (AUC 0.828).
结论:
- 新辅助性化学放射治疗,大量的血液流失和间切除是直肠静脉再泄漏的关键危险因素.
- 开发的诺姆图有效预测高风险患者,帮助临床决策.
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