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Updated: Jun 21, 2025

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整合素受体β7亚单元调解了暴露于过敏原的小鼠的呼吸道重塑和过敏反应

Miri Assayag1, Tahrir Obedeyah1, Avraham Abutbul1

  • 1Department of Pulmonary Medicine, Hadassah Medical Center and Faculty of Medicine, Hebrew University of Jerusalem, Ein Kerem, Jerusalem, Israel.

Respiratory research
|July 12, 2024
PubMed
概括

在喘模型中,β7整合素子单元和α4β7整合素复合物降低了气道过敏反应和重塑. 这是通过抑制纤维细胞激活而发生的,这种激活独立于氨酸细胞炎症.

关键词:
气道过度响应 气道过度响应喘 喘 是一种纤维母细胞细胞是如何形成的改造 改造 改造 改造 改造 改造 改造在 α4β7 整合蛋白中.

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