对因设备相关感染引起的败血症死亡率相关因素的分析
Ana Cristina Alba Amarante1, Arnildo Linck Junior2, Rosângela Aparecida Pimenta Ferrari3
1Programa de Posgrado en Fisiopatología Clínica y de Laboratorio, Departamento de Patología, Análisis Clínicos y Toxicológicos, Centro de Ciencias de la Salud, Universidad Estatal de Londrina, Londrina-Paraná, Brazil.
Anales de pediatria
|July 13, 2024
概括
从医院获得的感染 (HAI) 引起的败血症导致儿童的高死亡率,特别是那些患有耐卡巴胺细菌的儿童. 心脏病,癌症和血管压缩剂的使用增加了儿童重症监护室死亡的风险.
科学领域:
- 儿科重症监护医药 儿科重症监护医药
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 医疗保健相关感染 (HAI) 是致病率,死亡率和多抗药生物体传播的重要原因.
- 由于侵入性手术,重症监护室的儿童容易受到高危性感染和败血症的影响.
- 了解与HAI相关败血症死亡率相关的因素对于改善结果至关重要.
研究的目的:
- 分析与因医疗保健相关感染引起的败血症儿童死亡率相关的因素.
主要方法:
- 在儿科重症监护病房进行了一项病例对照研究.
- 该研究包括2014年1月至2018年12月期间入院的90名儿童.
- 病例是死于HAI相关性败血症的儿童,对照组是幸存者.
主要成果:
- 死亡率与年轻年龄 (≤12个月) 相关,并发症,先天性疾病,呼吸机相关肺炎和败血性休克.
- 多重回归确定了心脏病 (OR 12.48),抗卡巴胺细菌感染 (OR 31.51),癌症 (OR 58.23) 和上腺素治疗 (OR 13.14) 作为死亡的重要预测因素.
结论:
- 由于耐卡巴胺细菌的传染性败血症与这一儿科队列的高死亡率有关.
- 患有心脏病,癌症或需要血管压缩剂的儿童在与HAI相关的败血症中表现较差.
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