在食补充剂评估中应用体外消化模型
Justyna Ośko1, Katarzyna Nasierowska2, Małgorzata Grembecka1
1Department of Bromatology, Faculty of Pharmacy, Medical University of Gdańsk, Gen. J. Hallera Avenue 107, 80-416 Gdańsk, Poland.
Foods (Basel, Switzerland)
|July 13, 2024
概括
在体外消化模型对于评估食补充剂质量和成分生物可用性至关重要. 这些方法评估对肠道微生物群的影响,并有助于开发增强的,稳定的补充剂配方.
科学领域:
- 营养科学 营养科学
- 药理学 药理学是指药理学的学科.
- 食品科学 食品科学 食品科学
背景情况:
- 食补充剂是现代饮食中不可或缺的组成部分,需要强大的方法来评估它们的有效性.
- 越来越多地使用体外消化模型来研究补充剂成分的生物可用性,通常偏爱静态而不是动态方法.
- 了解补充剂,消化系统和肠道微生物群之间的相互作用对于产品开发至关重要.
研究的目的:
- 从2000年到2024年,审查体外方法在评估食补充剂中的应用.
- 突出体外模型在评估成分生物可访问性和稳定性方面的作用.
- 探索体外技术的使用在开发新的囊化策略的食补充剂.
主要方法:
- 对2000年至2024年的出版物进行系统的文献审查.
- 分析使用各种体外消化模型 (静态和动态) 的研究.
- 应用程序的分类,包括质量评估,生物可用性,微生物群的影响和新产品开发.
主要成果:
- 试验室方法广泛应用于评估含有多糖,蛋白质,元素,维生素和生物活性物质的食补充剂.
- 这些模型有效地确定了补充剂成分对消化道和微生物群的生物可访问性和影响.
- 该审查表明,体外技术在设计具有更好的成分稳定性和生物可用性的先进补充剂配方方面具有实用性.
结论:
- 在体外消化模型是对食补充剂全面评估的重要工具.
- 这些方法有助于评估成分的生物可访问性,生理影响以及开发创新的输送系统.
- 在体外模型的应用对于确保食补充剂的质量,有效性和稳定性至关重要.
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