在精神分裂症中脑部计算机断层扫描的发现:与第二代抗精神病药物和超益生菌血症的关系
Paula Simina Petric1,2, Petru Ifteni1,2, Andreea Violeta Popa1,2
1Facultatea de Medicină, Universitatea Transilvania din Brașov, Bulevardul Eroilor 29, 500036 Brașov, Romania.
Healthcare (Basel, Switzerland)
|July 13, 2024
概括
第二代抗精神病药物可能会导致精神分裂症患者的高益生菌性血症. 这项研究通过CT扫描没有发现脑瘤或乳腺瘤,但异常的乳腺素水平很常见,需要谨慎管理.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 放射学 放射学是一门学科.
背景情况:
- 精神分裂症影响全球人口的1%,由抗精神病药物管理.
- 第二代抗精神病药物可以在多达50%的患者中诱导超益生菌性血.
- 由于潜在的并发症和治疗坚持问题,高血糖性血症的管理至关重要.
研究的目的:
- 在接受第二代抗精神病药物的精神分裂症患者中调查大脑瘤,前乳腺瘤和结构性大脑变化的患病率.
- 为了将这些发现与益乳素水平和报告的副作用相关联.
主要方法:
- 一项对152名住院精神分裂症患者的横截面研究.
- 评估包括脑电脑断层扫描 (CT) 扫描,益生素水平评估和副作用监测.
- 在2020年1月至2024年3月期间收集的数据.
主要成果:
- 在53.95%的患者中发现了异常的前乳腺素水平,特别是女性接受RISPERIDONE和男性接受OLANZAPINE.
- 常见的副作用包括,头和体重增加 (61.78%报告).
- 通过CT扫描,没有检测到前乳腺瘤或其他脑瘤.
结论:
- 虽然第二代抗精神病药物与精神分裂症患者的高血糖过高率有关,但CT扫描无法检测到诸如益生菌瘤之类的结构性大脑异常.
- 抗精神病药物诱导的高血性乳糖血的有效管理对于患者的福祉和治疗坚持至关重要.
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