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Updated: Jun 21, 2025

A Kinetic Fluorescence-based Ca2+ Mobilization Assay to Identify G Protein-coupled Receptor Agonists, Antagonists, and Allosteric Modulators
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在cGAS-STING路径的激活剂和抑制剂

Xiaoxuan Yu1,2, Linxiang Cai3, Jingyue Yao4

  • 1Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, School of Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China.

Molecules (Basel, Switzerland)
|July 13, 2024
PubMed
概括

循环GMP-AMP合成酶 (cGAS) 刺激干扰素基因 (STING) 途径对于免疫治疗至关重要. 本综述详细介绍了cGAS-STING通路调节器,有助于开发新的向药物.

关键词:
激进分子的激进分子.cGAS-STING 的使用情况.药物设计 药物设计免疫疗法 免疫疗法抑制剂抑制剂的使用

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