药物过度使用的复杂形式头痛是慢性偏头痛的严重版本
Gülcan Göçmez Yılmaz1, Reza Ghouri2,3, Asena Ayça Özdemir4
1Department of Neurology, Mersin City Training and Research Hospital, Mersin 33110, Turkey.
Journal of clinical medicine
|July 13, 2024
概括
慢性偏头痛患者的药物过度使用头痛 (MOH) 与家族病史,更频繁/更强烈的头痛,双边疼痛,睡眠问题和情绪压力有关. 在MOH患者中,伴随性偏头痛症状也更常见.
科学领域:
- 神经学 神经学
- 头痛 医学 医学 医学
背景情况:
- 药物过度使用头痛 (MOH) 是慢性偏头痛 (CMs) 的已知并发症.
- MOH和CM之间的相互触发通常是公认的.
- 了解CM患者MOH发育的临床参数至关重要.
研究的目的:
- 在慢性偏头痛 (CM) 患者中调查与MOH发展相关的临床参数.
- 确定有助于MOH亚型分类的因素.
- 评估与MOH向复杂状态的进展相关的临床特征,包括精神病相关疾病.
主要方法:
- 在有或没有MOH的CM患者之间比较人口统计数据和偏头痛特征.
- 划分了一小组的MOH患者与精神病相关疾病 (抑郁症,焦虑症,睡眠障碍).
- 评估与MOH进展相关的临床特征.
主要成果:
- 在MOH亚组中,偏头痛家族病史的患病率较高 (p < 0.001,p = 0.036).
- 在MOH患者中,偏头痛发作的频率和严重程度增加,头痛持续时间更长,双侧疼痛和相关症状 (恶心,吐,光恐惧症,语音恐惧症,奥斯莫恐惧症).
- 在MOH和家族病史,头痛频率/严重程度,持续时间,阿托皮,睡眠障碍 (p <0.05) 之间发现了积极的相关性.
结论:
- 在CM患者中,MOH的患病率与偏头痛的家族病史,头痛频率/强度,双边疼痛,睡眠障碍和情绪压力具有积极的相关性.
- 偏头痛相关的症状在患有MOH和可能复杂的MOH的患者中更为普遍.
- 识别这些临床参数有助于理解和潜在地预防慢性偏头痛患者的MOH发展.
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