相关实验视频
Updated: Jun 21, 2025

08:56
Evaluating the Role of Mitochondrial Function in Cancer-related Fatigue
Published on: May 17, 2018
9.1K
患有COVID-19后病情和持续疲劳的患者的临床和生理变量
Maércio Santos1, Mariana Dorna1, Estefânia Franco2
1São Paulo State University (Unesp), Medical School, Distrito de Rubião Junior s/n, Botucatu 18618-970, São Paulo, Brazil.
Journal of clinical medicine
|July 13, 2024
概括
持续疲劳的COVID-19后病情与呼吸障碍,焦虑和肌肉力量降低的增加有关. 这些因素显著恶化了受影响个体的生活质量.
科学领域:
- 医学研究 医学研究
- 肺部病理学 肺部病理学
- 神经学 神经学
背景情况:
- 后COVID-19状态呈现多种症状,包括呼吸不全,认知问题和疲劳.
- 这些症状的潜在机制,特别是疲劳,需要进一步调查.
研究的目的:
- 评估COVID-19后患有持续疲劳的患者的临床和生理因素.
- 为了比较患有和没有持续性疲劳的患者,感染后一年.
主要方法:
- 在COVID-19感染一年后对77名患者的综合评估.
- 包括血清,代谢面板,螺旋计,呼吸障碍,生活质量,焦虑,抑郁,身体能力,身体组成和肌肉力量的评估.
- 患者被分为疲劳 (G1) 和非疲劳 (G2) 组.
主要成果:
- 患有持续疲劳 (G1) 的患者报告呼吸障碍 (BDI,mMRC分数) 增加,生活质量降低 (SGRQ分数).
- 在疲劳组中观察到更高的焦虑水平 (HADS-A) 和降低的外周和灵感肌肉力量 (手握,MIP).
- 在BDI (p<0.001),mMRC (p=0.002),SGRQ (p<0.001),HADS-A (p<0.001),手柄 (p=0.044) 和MIP (p<0.001) 中注意到了显著的差异.
结论:
- 持续的COVID-19后疲劳与呼吸障碍,焦虑,肌肉力量减少和生活质量受损的增加有关.
- 生活质量,焦虑程度和外围肌肉力量都会影响疲劳的严重程度.
- 生活质量的恶化与更大的呼吸障碍,较低的肌肉力量和减少的体力能力有关.
相关概念视频
Muscle Recovery and Fatigue
2.0K
Muscle fatigue refers to the decline in a muscle's ability to maintain the force of contraction after prolonged activity. It primarily stems from changes within muscle fibers. Even before experiencing muscle fatigue, one may feel tired and have the urge to stop the activity. This response, known as central fatigue, occurs due to changes in the central nervous system, namely the brain and spinal cord. While there is no single mechanism that induces fatigue, it may serve as a protective...
2.0K
Fatigue
180
Fatigue occurs when materials rupture under repeated or fluctuating loads, even at stress levels far below their static breaking strength. It typically results in brittle failure, even for ductile materials. It is a critical consideration in designing machines and structural components subjected to repetitive or varying loads. The nature of these loadings can range from fluctuating loads like unbalanced pump impellers causing vibrations to repeatedly bending a thin steel rod wire back and forth...
180
COPD: Pathogenesis and Clinical Features
257
Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
257
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
2.5K
Assessing and diagnosing Chronic Obstructive Pulmonary Disease (COPD) involves a detailed approach that includes a comprehensive review of medical history, physical examination, and a variety of diagnostic tests. This thorough evaluation is essential to ensure an accurate diagnosis and guide effective management strategies.
Medical History
Medical History
2.5K
Pneumonia II: Pathophysiology
247
The pathophysiology of pneumonia involves the following steps:
247
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
2.7K
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
2.7K

