系统性血压变化与发生大动脉狭窄症之间的关联
Hyun-Jung Kim1, Ji-Eon Kim2, Jae-Seung Jung2
1Department of Preventive Medicine, College of Medicine, Korea University, Seoul 02841, Republic of Korea.
Journal of clinical medicine
|July 13, 2024
概括
高血压变化 (BPV) 和高血压与大动脉狭窄 (AS) 风险增加有关. 管理血压稳定对于预防AS发病率至关重要.
科学领域:
- 心血管医学 心血管医学
- 高血压研究 高血压研究
- 流行病学 流行病学
背景情况:
- 研究了血压变化 (BPV) 和发生的大动脉狭窄 (AS) 之间的关联.
- 利用大规模的韩国国家医疗保险服务数据,从2002年至2019年.
研究的目的:
- 要确定静脉血压变化 (SBPV) 是否是大动脉狭窄症 (AS) 的独立预测因素.
- 评估与不同水平的SBPV相关的AS风险.
主要方法:
- 在三年内连续三次读取超过900万个人的年度SBPV数据.
- 将SBPV分为五种类型,最高的代表显著的血压波动.
- 进行了生存分析,以评估SBPV五分位数和事件AS之间的关联.
主要成果:
- 更高的SBPV独立地与AS风险增加有关.
- 在SBPV的最高五分位数中,AS发病率显著增加了1.39的危险比率 (HR) (p < 0.001).
- 高血压和升高的SBPV被确定为AS的独立预测因素.
结论:
- 较高的缩血压变化 (SBPV) 是发生大动脉狭窄症 (AS) 的重要危险因素.
- 维持稳定的血压,以及管理高血压,对于AS预防至关重要.
- 强调监测BPV在心血管风险评估中的临床重要性.
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