怀孕期间的厌恶敏感性与内源性类固醇之间的关联:一项纵向研究
Šárka Kaňková1, Daniela Dlouhá1, Jana Ullmann1
1Department of Philosophy and History of Science, Faculty of Science, Charles University, Viničná 7, 128 44 Prague, Czech Republic.
International journal of molecular sciences
|July 13, 2024
概括
怀孕增加了厌恶的敏感性,与上升的类固醇激素水平有关. 这项研究发现,在怀孕期间,厌恶感和各种类固醇 (包括和皮质醇) 之间存在关联.
科学领域:
- 生殖生物学 生殖生物学
- 神经内分泌学神经内分泌学
- 心理神经免疫学 心理神经免疫学
背景情况:
- 厌恶敏感性是一种保护我们免受病原体影响的情绪.
- 在怀孕期间,厌恶感通常会加剧.
- 荷尔蒙变化,包括免疫标记物和孕激素,与怀孕相关的厌恶变化有关.
研究的目的:
- 研究孕妇类固醇激素水平与厌恶敏感性之间的关联.
- 探索这些关联如何在怀孕的三个月内发生变化.
主要方法:
- 对179名孕妇进行了前性纵向研究.
- 对血清类固醇度的分析.
- 使用基于文本的问卷在第一和第三个季度测量厌恶的灵敏度.
主要成果:
- 在 Δ4 和 Δ5 路径中发现了厌恶敏感性和 C19 类固醇 (,DHEA,androstenedione) 和它们的前体之间的正相关性.
- 观察到与5α/β降低的C19类固醇代谢物,17-hydroxypregnanolone和第一季度的一些雌激素的关联.
- 第三个三个月的发现包括与皮质醇和免疫保护性 Δ5 C19 7α/β-基类固醇的积极关联.
结论:
- 怀孕期间的厌恶敏感性与免疫调节类固醇具有积极的相关性.
- 在第三个三个月,厌恶的敏感性与类固醇有关,可能与母亲的焦虑有关.
- 怀孕期间的荷尔蒙变化显著影响了厌恶的敏感性,突出了复杂的相互作用.
关键词:
7α/β-基-原体的存在这就是DHEA,DHEA.素二醇是一种素二醇.行为免疫系统 行为免疫系统皮质醇是一种皮质醇.恶心 恶心 恶心 恶心雌激素是一种雌激素.怀孕 怀孕 怀孕 怀孕 怀孕类固醇类固醇是什么测试剂 测试剂 测试剂 测试剂更多相关视频
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