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Updated: Jun 21, 2025

A Protocol for Computer-Based Protein Structure and Function Prediction
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G蛋白结合受体-连接体姿势和功能类预测

Gregory L Szwabowski1, Makenzie Griffing1, Elijah J Mugabe1

  • 1Department of Chemistry, University of Memphis, Memphis, TN 38152, USA.

International journal of molecular sciences
|July 13, 2024
PubMed
概括

预测与G蛋白结合受体 (GPCRs) 的药物相互作用对于药物发现至关重要. 这项研究发现,虽然连接体相互作用指纹提供了轻微的好处,但随机森林分类器准确地预测了GPCRs的连接体功能.

关键词:
G蛋白结合受体 (GPCR) 是一种停靠的对接方式互动指纹 互动指纹机器学习是机器学习.随机森林分类器随机森林分类器

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