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Updated: Jun 21, 2025

Functionalization of Atomic Force Microscope Cantilevers with Single-T Cells or Single-Particle for Immunological Single-Cell Force Spectroscopy
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UniCAR T细胞功率 - 适应器分子和适应器CAR T细胞之间的亲和关系问题?

Hugo Boutier1, Liliana R Loureiro1, Lydia Hoffmann1

  • 1Department of Radioimmunology, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf (HZDR), 01328 Dresden, Germany.

International journal of molecular sciences
|July 13, 2024
PubMed
概括

这项研究调查了适应器CAR系统,发现改变UniCAR表位亲和力不会显著影响T细胞对抗癌症点的功效. 这表明更高的亲和力对适配器CAR疗效并不至关重要.

关键词:
E5B9 UniCAR 的表位是 E5B9 的表位.纤维细胞激活蛋白 (FAP) 是一种激活蛋白.在UniCAR的T细胞中.适配器 汽车平台的适配器癌症免疫疗法免疫疗法

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