相关实验视频
Updated: Jun 21, 2025

07:44
A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
328
在COVID-19肺栓塞后心肺复杂症
Carla Suarez-Castillejo1,2, Néstor Calvo3, Luminita Preda3
1Servicio de Neumología, Hospital Universitario Son Espases, 07120 Palma de Mallorca, Spain.
International journal of molecular sciences
|July 13, 2024
概括
肺栓塞 (PE) 并没有使住院COVID-19患者的中期结果恶化. 退院后肺功能减弱和放射性异常是常见的,但PE没有增加这些风险.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 肺栓塞 (PE) 是已知的COVID-19并发症,但其对中期患者结果的影响尚不清楚.
- 了解这些结果对于管理COVID-19后的护理和识别风险人群至关重要.
研究的目的:
- 描述和比较住院COVID-19患者与没有PE的中期结果.
- 为了确定COVID-19后肺部异常和扩散能力受损的预测因素.
主要方法:
- 141名住院COVID-19患者的队列接受了肺功能测试,心声学和CT肺血管学.
- 分析了血液中的生物标志物,并对患者进行了中位数6个月的随访.
- 开发了COVID-19后放射性肺异常 (PCRLA) 的预测得分.
主要成果:
- 55.2%的患者患有PCRLA,67.6%的患者患有一氧化碳扩散能力受损 (DLCOc).
- 在7.3%的患者中存在PE,与非PE患者相比,结果没有显著差异.
- 年龄,临床严重程度,表面活性蛋白-D,C-反应蛋白,红细胞分布宽度和IL-10与DLCOc的减少有关. 开发了一个PCRLA预测得分.
结论:
- 降低DLCOc和PCRLA在COVID-19住院后很常见,无论PE是否存在.
- PE似乎不会增加这些中期并发症的风险.
- 为PCRLA开发了一个验证的预测得分,有助于风险分层.
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