高应变动态负荷对HEMA-DMAEMA水凝存储模块和时间依赖性的影响
Kimberly Cook-Chennault1,2, Sharmad Anaokar1, Alejandra M Medina Vázquez3
1Mechanical and Aerospace Engineering Department, Rutgers University, Piscataway, NJ 08854-5750, USA.
Polymers
|July 13, 2024
概括
这项研究研究了在高张力率下水凝的机械性能. 增加的应变降低了水凝的刚性,揭示了对生物医学应用至关重要的网络破坏.
科学领域:
- 生物材料科学 生物材料科学
- 聚合物化学 聚合物化学
- 机械工程 机械工程
背景情况:
- 水凝对于药物输送,组织工程和生物传感器至关重要.
- 关于在高应变动态负荷下水凝机械行为的数据有限.
- 了解这种行为对于先进的生物医学设计和数值建模至关重要.
研究的目的:
- 在高应变动态压缩下描述HEMA-DMAEMA水凝的机械性能.
- 为了研究应用应变和水凝粘弹性反应之间的关系.
- 为改善水凝设计和计算模型提供经验数据.
主要方法:
- 通过光聚合合成HEMA-DMAEMA的水凝.
- 使用高压缩振荡负载进行了动态机械分析.
- 长时间 (72小时至15天) 应用了50%,60%和70%的应变率.
主要成果:
- 储存和损失模块随着变压率的增加而减少.
- 随着时间的推移,观察到模块的减少,这表明网络退化.
- 观察到的变化归因于网络中断,链裂和塑性变形.
结论:
- 高拉伸率显著影响水凝的机械性能.
- 在极端变形下,水凝网络的完整性受到损害.
- 这些发现对于预测动态生物医学应用中的水凝性能至关重要.
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