准备和结构-属性关系研究用于骨组织工程的压电导电复合聚合物纳米纤维材料
Zhengyang Jin1, Suiyan Wei2, Wenyang Jin1
1School of Mechanical Engineering, Xinjiang University, Urumchi 830017, China.
Polymers
|July 13, 2024
概括
研究人员开发了新的压电导电聚合物纳米纤维,以模仿骨.
科学领域:
- 生物材料科学 生物材料科学
- 组织工程是组织工程.
- 聚合物纳米纤维 聚合物纳米纤维
背景情况:
- 骨组织工程需要模仿骨的压电和导电性的材料.
- 现有的材料往往缺乏有效修复骨所需的电活性特性.
研究的目的:
- 开发Janus,跨网络和同轴结构的压电导电聚合物纳米纤维.
- 为了模仿骨的压电,并促进电信号传导,以修复骨组织.
- 研究结构特征对纤维电活性的影响.
主要方法:
- 聚乙烯化物的电与减少的氧化石墨烯和聚烯.
- 使用SEM,TEM和FTIR进行表征.
- 用d33米和四探针方法评估电活性; 机械和生物相容性测试.
主要成果:
- 在纳米纤维中成功整合了压电和导电相.
- 简斯结构的纳米纤维表现出优越的电活性 (d33: 24.5 pC/N,导电性: 6.78 × 10-2 S/m).
- 高度 (>70%) 和机械强度超过骨周;优良的生物相容性和细胞增殖促进.
结论:
- 亚努斯结构的压电导电纳米纤维显示了骨组织工程的重大前景.
- 开发的材料具有理想的机械,电气和生物特性,适用于骨再生应用.
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