预防性抗生素在sialendoscopy:一个随机临床试验
Carlos M Chiesa-Estomba1,2,3, Alvaro Sanchez-Barrueco4,5, Giovanni Cammaroto6,7
1Department of Otorhinolaryngology, Osakidetza Donostia University Hospital, Biodonostia Research Institute, San Sebastian, 20014, Spain. chiesaestomba86@gmail.com.
常规的预防性抗生素不需要用于sialendoscopy程序. 这项研究发现,接受抗生素和不接受抗生素的患者之间的术后感染没有显著差异,这表明抗生素使用的潜在减少.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 手术感染预防 手术感染预防
背景情况:
- 内镜检查程序通常涉及常规抗生素预防.
- 支持这种做法减少术后感染的证据有限.
研究的目的:
- 为了评估预防性抗生素在sialendoscopy的必要性.
- 为此过程中使用抗生素提供基于证据的指导.
主要方法:
- 进行了一项前性,随机,双盲,受控的临床试验.
- 包括80名接受内镜检查的患者.
主要成果:
- 感染率为5.6%的预防和9.1%没有.
- 两组之间感染事件的差异没有统计学意义 (p=0.556).
结论:
- 常规的预防性抗生素可能不需要用于sialendoscopy.
- 研究结果支持减少不必要的抗生素使用,解决耐药性和不良反应.
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