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Updated: Jun 21, 2025

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帕金森病相关SNP rs329648对MicroRNA-4697-3p的调节及其对SNCA112 mRNA的影响

Myungsik Yoo1, Klaudia Bunkowski1, Andrew Lie1

  • 1RWJMS Institute for Neurological Therapeutics, Department of Neurology, Rutgers -Robert Wood Johnson Medical School, Piscataway, NJ, 08854, USA.

Molecular biology reports
|July 13, 2024
PubMed
概括

帕金森病 (PD) 的遗传变体 (rs329648) 增加了miR-4697-3p,促进了α-synuclein聚合和细胞死亡. 这一发现揭示了PD的发病因和潜在的治疗点.

关键词:
阿尔法-同核素是什么阿尔法-同核素全基因组关联研究 (GWAS)帕金森病是帕金森氏症的一种疾病.在SNCA112 mRNA中.在 miR-4697-3pp 中使用.需要 rs32963838 的钱.

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