心率变化作为手术内自主神经系统恒温的预测因素
Ole C Keim1, Lennart Bolwin2, Robert E Feldmann1
1Department of Anesthesiology, Pain Center, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Germany.
Journal of clinical monitoring and computing
|July 13, 2024
概括
心率变化 (HRV) 可以监测在sevoflurane麻醉期间的催眠深度. 这项研究发现HRV与毒品趋势指数和麻醉水平相关,为自主神经系统功能提供了洞察力.
科学领域:
- 麻醉学 麻醉学
- 神经科学是一个神经科学.
- 心脏病学 心脏病学
背景情况:
- 监测催眠深度对于全身麻醉期间的患者安全至关重要.
- 麻醉品趋势指数 (NI) 是基于EEG的催眠深度标记.
- 心率变化 (HRV) 反映了自主神经系统的活动.
研究的目的:
- 为了研究手术期间塞沃兰的HRV,NI和最小气泡度 (MAC) 之间的一致性.
- 评估HRV作为潜在的催眠深度和麻醉效果的替代标记.
主要方法:
- 一项涉及31名接受机器人辅助激进前列腺切除术的男性患者的横截面研究.
- 在手术期间记录HRV,NI和sevoflurane MAC.
- 使用重复测量的相关性 (rmcorr) 的统计分析.
主要成果:
- 在NI和HRV参数 (SDNN,LF,LF/HF比率) 之间发现了显著的相关性.
- MAC显示与HRV参数 (SDNN,LF,LF/HF比率) 和NI的显著负相关性.
- 毒品趋势指数与MAC有负相关性 (rrm = -0.49,p < 0.001).
结论:
- HRV反映了Narcotrend指数的趋势,表明其在监测催眠深度方面的实用性.
- HRV反映了自主神经系统对sevoflurane麻醉的反应.
- 在全身麻醉期间,HRV可以提供有关自主神经系统恒温的宝贵信息.
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