基本饮食作为一种治疗方式:综合性审查
Jason Nasser1,2, Sepideh Mehravar1, Mark Pimentel1,2
1Medically Associated Science and Technology (MAST) Program, Cedars-Sinai, 700 N. San Vicente Blvd, Suite G271, West Hollywood, CA, 90069, USA.
Digestive diseases and sciences
|July 13, 2024
概括
元素饮食在各种胃肠道疾病中显示出临床益处,尽管由于食感和成本问题而不足利用. 需要进一步的试验来确认它们的有效性和最佳使用在管理这些条件.
科学领域:
- 胃肠道学和营养学
- 饮食干预 饮食干预
- 临床有效性 临床有效性
背景情况:
- 50多年来,元素饮食已经用于各种疾病.
- 尽管有经过验证的机制,但它们的使用受到可口性,成本,获取和认识的限制.
- 需要进行系统审查,以巩固当前关于它们的配方,机制,应用和耐受性的知识.
研究的目的:
- 系统地审查有关元素饮食的文献.
- 为了总结配方,作用机制,临床应用和胃肠道疾病中的耐受性.
- 确定未来研究和临床应用的领域.
主要方法:
- 系统的文献搜索和审查.
- 分析配方变异性,机制,临床应用和耐受性数据.
- 综合现有研究的证据,承认诸如缺乏大型前性试验等局限性.
主要成果:
- 元素饮食在乙性食管炎,炎症性肠病,小肠细菌过度生长和腹腔疾病中显示出临床益处.
- 机制包括无过敏原含量,高吸收率和抗炎作用.
- 由于口味不佳而引起的高口服不耐受性 (高达40%),尽管在耐受时,不良事件很少发生. 限制包括成本,访问和社会限制.
结论:
- 元素饮食对胃肠道疾病具有潜在的高度有效性,在耐受时具有轻微的副作用.
- 使用障碍包括可口性,成本,访问和社会限制.
- 未来的临床试验对于确定它们在管理特定胃肠道疾病中的作用至关重要.
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